RNA Binding Motif Protein 11 (RBM11)

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Splicing regulator RBM11

RNA Binding Motif Protein 11 (RBM11)
RBM11 is moderately expressed, only 36.0% of the average gene in this release. RBM11 contains 7 different gt-ag introns. Transcription produces 7 different mRNAs, 5 alternatively spliced variants and 2 unspliced forms. There are 5 validated alternative polyadenylation sites. The mRNAs appear to differ by presence or absence of 2 cassette exons, overlapping exons with different boundaries. 5 spliced mRNAs putatively encode good proteins, altogether 5 different isoforms (4 complete, 1 partial), some containing RNA-binding region RNP-1 (RNA recognition motif). The remaining 2 mRNA variants (2 unspliced) appear not to encode good proteins. There is one article specifically referring to this gene in PubMed. Proteins are expected to have molecular functions and to localize in nucleus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Motif Protein 11 (RBM11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Motif Protein 11 (RBM11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Motif Protein 11 (RBM11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Motif Protein 11 (RBM11) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Motif Protein 11 (RBM11) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Motif Protein 11 (RBM11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Motif Protein 11 (RBM11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Motif Protein 11 (RBM11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Motif Protein 11 (RBM11) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Motif Protein 11 (RBM11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Motif Protein 11 (RBM11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Motif Protein 11 (RBM11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Motif Protein 11 (RBM11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Motif Protein 11 (RBM11) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Motif Protein 11 (RBM11) ELISA Kit Customized Service Offer
  1. "The DNA sequence of human chromosome 21." Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Annotation of human chromosome 21 for relevance to Down syndrome: gene structure and expression analysis."Genomics 79:833-843(2002) [PubMed] [Europe PMC] [Abstract]
  5. "Juxtacentromeric region of human chromosome 21: a boundary between centromeric heterochromatin and euchromatic chromosome arms."Gene 312:41-50(2003) [PubMed] [Europe PMC] [Abstract]
  6. "The RNA recognition motif protein RBM11 is a novel tissue-specific splicing regulator."Nucleic Acids Res. 40:1021-1032(2012) [PubMed] [Europe PMC] [Abstract]
  7. "Crystal structure of RRM-domain derived from human putative RNA-binding protein 11."Submitted (FEB-2009) to the PDB data bank