≡

Melanoma Antigen Family B3 (MAGEB3)

[Edit]

CT3.5; Cancer/Testis Antigen Family 3, Member 5

Melanoma Antigen Family B3 (MAGEB3)
CCC Q290
HGNC 6810
MGI 2148172
PubMed 7757970
RGD 1562343
UniProt O15480
MAGEB3is a MAGE-B subfamily member of the MAGE gene family. MAGE family member proteins direct the expression of tumor antigens recognized on a human melanoma by autologous cytolytic T lymphocytes. There are two known clusters of MAGE genes on chromosome X. The members of the MAGE-A subfamily are located in the Xq28 region, while the members of the MAGE-B subfamily are clustered in the Xp21 region.
Lurquin et al. (1997) identified the MAGEB3 gene within a cluster of 4 MAGE-related genes in Xp21.3. See MAGEB1. RT-PCR analysis found that MAGEB3 is expressed in testis; it was expressed in 2 of 6 examined testicular tumors. The deduced MAGEB3 protein has 346 amino acids.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Melanoma Antigen Family B3 (MAGEB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanoma Antigen Family B3 (MAGEB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanoma Antigen Family B3 (MAGEB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanoma Antigen Family B3 (MAGEB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanoma Antigen Family B3 (MAGEB3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Melanoma Antigen Family B3 (MAGEB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanoma Antigen Family B3 (MAGEB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanoma Antigen Family B3 (MAGEB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanoma Antigen Family B3 (MAGEB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanoma Antigen Family B3 (MAGEB3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Melanoma Antigen Family B3 (MAGEB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanoma Antigen Family B3 (MAGEB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanoma Antigen Family B3 (MAGEB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanoma Antigen Family B3 (MAGEB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanoma Antigen Family B3 (MAGEB3) ELISA Kit Customized Service Offer
  1. "Two members of the human MAGEB gene family located in Xp21.3 are expressed in tumors of various histological origins."Genomics 46:397-408(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]