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Melanoma Antigen Family B2 (MAGEB2)

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DAM6; MAGE-XP-2; CT3.2; DSS/AHC Critical Interval MAGE Superfamily 6; Cancer/Testis Antigen Family 3, Member 2

Melanoma Antigen Family B2 (MAGEB2)
CCC Q289
HGNC 6809
MGI 2684887
PubMed 23029077
RGD 1562439
UniProt O15479
Wiki MAGEB2
MAGEB2 is a member of the MAGEB gene family. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. MAGEB2 is expressed in testis and placenta, and in a significant fraction of tumors of various histologic types. Expression could be induced by a demethylating agent, suggesting that the activation of MAGEB2 in tumors results from a demethylation process.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Melanoma Antigen Family B2 (MAGEB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanoma Antigen Family B2 (MAGEB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanoma Antigen Family B2 (MAGEB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanoma Antigen Family B2 (MAGEB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanoma Antigen Family B2 (MAGEB2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Melanoma Antigen Family B2 (MAGEB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanoma Antigen Family B2 (MAGEB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanoma Antigen Family B2 (MAGEB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanoma Antigen Family B2 (MAGEB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanoma Antigen Family B2 (MAGEB2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Melanoma Antigen Family B2 (MAGEB2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Melanoma Antigen Family B2 (MAGEB2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Melanoma Antigen Family B2 (MAGEB2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Melanoma Antigen Family B2 (MAGEB2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Melanoma Antigen Family B2 (MAGEB2) ELISA Kit Customized Service Offer
  1. "A family of rapidly evolving genes from the sex reversal critical region in Xp21."Mamm. Genome 6:571-580(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Two members of the human MAGEB gene family located in Xp21.3 are expressed in tumors of various histological origins."Genomics 46:397-408(1997) [PubMed] [Europe PMC] [Abstract]
  3. "MAGE Xp-2: a member of the MAGE gene family isolated from an expression library using systemic lupus erythematosus sera."Mol. Genet. Metab. 63:3-13(1998) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  7. "MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases."Mol. Cell 39:963-974(2010) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]