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Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2)

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COXVIIa-L; COX7AL; Cytochrome c oxidase subunit VIIa-liver/heart; Cytochrome c oxidase subunit 7A2, mitochondrial

Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2)
CCC Q107
HGNC 2288
MGI 1316715
PubMed 22365974
RGD 68365
UniProt P14406
Wiki COX7A2
This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex.
COX7A2 encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cytochrome C Oxidase Subunit VIIa Polypeptide 2 (COX7a2) ELISA Kit Customized Service Offer
  1. "Sequence of a cDNA specifying subunit VIIa of human cytochrome c oxidase."Nucleic Acids Res. 17:7107-7107(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Isolation and sequence of the human cytochrome c oxidase subunit VIIaL gene."Biochim. Biophys. Acta 1492:252-258(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Subunits VIIa,b,c of human cytochrome c oxidase. Identification of both 'heart-type' and 'liver-type' isoforms of subunit VIIa in human heart."Eur. J. Biochem. 203:193-199(1992) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase."Genome Biol. 13:RESEARCH0012.1-RESEARCH0012.14(2012) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]