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Ornithine Aminotransferase Like Protein 1 (OATL1)

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TBC1D25; TBC1 Domain Family Member 25

Ornithine Aminotransferase Like Protein 1 (OATL1)
CCC P817
HGNC 8092
MGI 2444862
PubMed 21383079
RGD 1559711
UniProt Q3MII6
Based on sequence analysis, Bernards (2003) determined that the TBC1D25 gene, earlier designated OATL1, is a member of a large superfamily of Ras GTPase activating proteins. TBC1D25 encodes a 688-amino acid protein with a TBC domain. Bernards (2003) noted that TBC domain proteins contain a 200- to 240-amino acid Ypt/RabGAP catalytic domain found in the human TRE2 oncogene and the yeast Bub2p and Cdc16 spindle checkpoint proteins.Barrett et al. (1987) identified 2 gene sequences at Xp11.2 that were similar to the ornithine aminotransferase (OAT) sequence. Lafreniere et al. (1991) refined the localization of the X-linked sequences homologous to OAT: OATL1 mapped to Xp11.3-p11.23 (distal), while OATL2 mapped to Xp11.22-p11.21 (proximal)

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ornithine Aminotransferase Like Protein 1 (OATL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ornithine Aminotransferase Like Protein 1 (OATL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ornithine Aminotransferase Like Protein 1 (OATL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ornithine Aminotransferase Like Protein 1 (OATL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ornithine Aminotransferase Like Protein 1 (OATL1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ornithine Aminotransferase Like Protein 1 (OATL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ornithine Aminotransferase Like Protein 1 (OATL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ornithine Aminotransferase Like Protein 1 (OATL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ornithine Aminotransferase Like Protein 1 (OATL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ornithine Aminotransferase Like Protein 1 (OATL1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ornithine Aminotransferase Like Protein 1 (OATL1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ornithine Aminotransferase Like Protein 1 (OATL1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ornithine Aminotransferase Like Protein 1 (OATL1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ornithine Aminotransferase Like Protein 1 (OATL1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ornithine Aminotransferase Like Protein 1 (OATL1) ELISA Kit Customized Service Offer
  1. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  4. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  6. "OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation."J. Cell Biol. 192:839-853(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]