≡

RAB27B, Member RAS Oncogene Family (RAB27B)

[Edit]

C25KG; Ras-related protein Rab-27B

RAB27B, Member RAS Oncogene Family (RAB27B)
CCC P768
HGNC 9767
MGI 1931295
PubMed 20484105
RGD 620114
UniProt O00194
Members of the Rab protein family are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking. The predicted 218-amino acid RAB27B protein is 71% identical to RAB27A. RAB3A and RAB3B, the most closely related human Rab proteins, share only 41 to 44% identity with RAB27A and RAB27B, suggesting that the RAB27 proteins are members of a distinct subfamily.
Northern blot analysis revealed that RAB27B is expressed significantly only in testis, in which the predominant transcript was 1.4 kb in size. An 8-kb mRNA of unknown origin was detected in many tissues. Recombinant RAB27A and RAB27B exhibited GTP-binding activity in vitro.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP768Hu01 Recombinant RAB27B, Member RAS Oncogene Family (RAB27B) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to RAB27B, Member RAS Oncogene Family (RAB27B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB27B, Member RAS Oncogene Family (RAB27B) Polyclonal Antibody Customized Service Offer
Assay Kits SEP768Hu ELISA Kit for RAB27B, Member RAS Oncogene Family (RAB27B) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB27B, Member RAS Oncogene Family (RAB27B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB27B, Member RAS Oncogene Family (RAB27B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB27B, Member RAS Oncogene Family (RAB27B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB27B, Member RAS Oncogene Family (RAB27B) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB27B, Member RAS Oncogene Family (RAB27B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB27B, Member RAS Oncogene Family (RAB27B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB27B, Member RAS Oncogene Family (RAB27B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB27B, Member RAS Oncogene Family (RAB27B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB27B, Member RAS Oncogene Family (RAB27B) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB27B, Member RAS Oncogene Family (RAB27B) ELISA Kit Customized Service Offer
  1. "Molecular cloning and characterization of rab27a and rab27b, novel human rab proteins shared by melanocytes and platelets."Biochem. Mol. Med. 60:27-37(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Chromosomal mapping, gene structure and characterization of the human and murine RAB27B gene."BMC Genet. 2:2-2(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Purification, identification, and characterization of two GTP-binding proteins with molecular weights of 25,000 and 21,000 in human platelet cytosol. One is the rap1/smg21/Krev-1 protein and the other is a novel GTP-binding protein."J. Biol. Chem. 264:17000-17005(1989) [PubMed] [Europe PMC] [Abstract]
  6. , Submitted (NOV-2005) to UniProtKB
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "The crystal structure of human RAB27B."Submitted (FEB-2009) to the PDB data bank