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RNA Binding Protein S1, Serine Rich Domain (RNPS1)

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LDC2; SR-related protein LDC2

RNA Binding Protein S1, Serine Rich Domain (RNPS1)
CCC P724
HGNC 10080
MGI 97960
PubMed 22388736
RGD 1307522
UniProt Q15287
Wiki RNPS1
RNPS1 encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance.This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein. RNPS1 protein has long stretches that are 100% identical to the mouse protein. RNPS1 has a long N-terminal ser-rich (SR) region; a 90-residue RNA recognition motif that contains RNP1 and RNP2 submotifs; an SR splicing protein motif; 2 arg-rich RNA-binding domains; and a C-terminal nuclear localization signal. Northern blot analysis revealed ubiquitous expression of a 2.4-kb RNPS1 transcript.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Protein S1, Serine Rich Domain (RNPS1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Protein S1, Serine Rich Domain (RNPS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Protein S1, Serine Rich Domain (RNPS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Protein S1, Serine Rich Domain (RNPS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Protein S1, Serine Rich Domain (RNPS1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Protein S1, Serine Rich Domain (RNPS1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Protein S1, Serine Rich Domain (RNPS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Protein S1, Serine Rich Domain (RNPS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Protein S1, Serine Rich Domain (RNPS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Protein S1, Serine Rich Domain (RNPS1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RNA Binding Protein S1, Serine Rich Domain (RNPS1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RNA Binding Protein S1, Serine Rich Domain (RNPS1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RNA Binding Protein S1, Serine Rich Domain (RNPS1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RNA Binding Protein S1, Serine Rich Domain (RNPS1) CLIA Kit Customized Service Offer
n/a ELISA Kit for RNA Binding Protein S1, Serine Rich Domain (RNPS1) ELISA Kit Customized Service Offer
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  21. "The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the nonsense mediated decay pathway."Nucleic Acids Res. 35:4542-4551(2007) [PubMed] [Europe PMC] [Abstract]
  22. "Assembly and mobility of exon-exon junction complexes in living cells."RNA 15:862-876(2009) [PubMed] [Europe PMC] [Abstract]
  23. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
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