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Ribosomal Protein L11 (RPL11)

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CLL-associated antigen KW-12; 60S ribosomal protein L11

Ribosomal Protein L11 (RPL11)
CCC P722
HGNC 10301
MGI 1914275
PubMed 24341334
RGD 1308681
UniProt P62913
Wiki RPL11
RPL11 encodes a ribosomal protein that is a component of the 60S subunit. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternative splice variants encoding different isoforms may exist, but they have not been fully characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.RPL11-mediated p53 induction in human cell lines was a general response to inhibition of 40S or 60S ribosome biogenesis and did not require nucleolar disruption. Inhibition of 40S ribosome biogenesis led to increased ribosome-free RPL11 due to derepression of the polypyrimidine tract at its 5-prime transcriptional start site (the 5-prime TOP), followed by increased RPL11 mRNA translation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribosomal Protein L11 (RPL11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribosomal Protein L11 (RPL11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribosomal Protein L11 (RPL11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribosomal Protein L11 (RPL11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribosomal Protein L11 (RPL11) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribosomal Protein L11 (RPL11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribosomal Protein L11 (RPL11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribosomal Protein L11 (RPL11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribosomal Protein L11 (RPL11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribosomal Protein L11 (RPL11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribosomal Protein L11 (RPL11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribosomal Protein L11 (RPL11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribosomal Protein L11 (RPL11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribosomal Protein L11 (RPL11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribosomal Protein L11 (RPL11) ELISA Kit Customized Service Offer
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  4. , Submitted (NOV-2005) to UniProtKB
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  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  12. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  14. "Structures of the human and Drosophila 80S ribosome."Nature 497:80-85(2013) [PubMed] [Europe PMC] [Abstract]
  15. "Identification of mutations in the ribosomal protein L5 (RPL5) and ribosomal protein L11 (RPL11) genes in Czech patients with Diamond-Blackfan anemia."Hum. Mutat. 30:321-327(2009) [PubMed] [Europe PMC] [Abstract]