Proline-rich peptide sequences have been shown to play important roles in protein-protein interactions that occur in signal transduction pathways. Specific proline-rich consensus sequences that bind SH3 domains have been identified.
The predicted 114-amino acid SH3BGRL protein has a potential cell attachment sequence. A proline-rich sequence containing an SH3-binding motif is present in the middle of the protein. The SH3BGRL protein shares 60% identity with the proline-rich central region of SH3BGR. Northern blot analysis detected a single SH3BGRL transcript of approximately 1.9 kb that was present in all tissues examined.Mouse cDNA encoding a deduced protein that is 95% identical to human SH3BGRL.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPP692Hu01 | Recombinant SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | MAP692Hu21 | Monoclonal Antibody to SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | WB; IHC; ICC; IP. |
PAP692Hu01 | Polyclonal Antibody to SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | WB; IHC; ICC; IP. | |
Assay Kits | SEP692Hu | ELISA Kit for SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for SH3 Domain Binding Glutamic Acid Rich Protein Like Protein (SH3BGRL) | ELISA Kit Customized Service Offer |
- "Identification and characterization of a new human gene encoding a small protein with high homology to the proline-rich region of the SH3BGR gene."Biochem. Biophys. Res. Commun. 247:302-306(1998) [PubMed] [Europe PMC] [Abstract]
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- "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "Crystal structure of human SH3BGRL protein: the first structure of the human SH3BGR family representing a novel class of thioredoxin fold proteins."Proteins 61:213-216(2005) [PubMed] [Europe PMC] [Abstract]
- "Solution structure of the SH3 domain-binding glutamic acid-rich-like protein."Submitted (APR-2005) to the PDB data bank