Solute Carrier Family 4, Member 9 (SLC4A9)
[Edit]AE4; SBC5; Anion exchange protein 4; Sodium bicarbonate cotransporter 5
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SLC4A9 contains 945 amino acids and has a calculated molecular mass of 104 kD. AE4 has 14 transmembrane domains and intracellular N and C termini. It contains an N-terminal leucine zipper motif, multiple intracellular phosphorylation sites, and 2 extracellular N-glycosylation sites. It shares 84% amino acid identity with rabbit Ae4, a sodium-independent Cl-/HCO3- exchanger located on the apical membrane of beta-intercalated kidney cells. SDS-PAGE following cell-free translation revealed AE4 at an apparent molecular mass of 100 kD. AE4 did not appear to be N-glycosylated. Northern blot analysis detected expression in kidney only.The major splice variant encodes a 990-amino acid protein that shares 49% and 48% identity with SLC4A4 and SLC4A7, respectively.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Solute Carrier Family 4, Member 9 (SLC4A9) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Solute Carrier Family 4, Member 9 (SLC4A9) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Solute Carrier Family 4, Member 9 (SLC4A9) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Solute Carrier Family 4, Member 9 (SLC4A9) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Solute Carrier Family 4, Member 9 (SLC4A9) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Solute Carrier Family 4, Member 9 (SLC4A9) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Solute Carrier Family 4, Member 9 (SLC4A9) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Solute Carrier Family 4, Member 9 (SLC4A9) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Solute Carrier Family 4, Member 9 (SLC4A9) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Solute Carrier Family 4, Member 9 (SLC4A9) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Solute Carrier Family 4, Member 9 (SLC4A9) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Solute Carrier Family 4, Member 9 (SLC4A9) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Solute Carrier Family 4, Member 9 (SLC4A9) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Solute Carrier Family 4, Member 9 (SLC4A9) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Solute Carrier Family 4, Member 9 (SLC4A9) | ELISA Kit Customized Service Offer |
- "Human BTR1, a new bicarbonate transporter superfamily member and human AE4 from kidney."Biochem. Biophys. Res. Commun. 282:1103-1109(2001) [PubMed] [Europe PMC] [Abstract]
- "A novel sodium bicarbonate cotransporter-like gene in an ancient duplicated region: SLC4A9 at 5q31."Genome Biol. 2:RESEARCH0011.1-RESEARCH0011.13(2001) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]