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Vacuolar Protein Sorting 72 (VPS72)

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TCFL1; YL-1; YL1; Swc2; Transcription Factor-Like 1; Vacuolar protein sorting-associated protein 72 homolog

Vacuolar Protein Sorting 72 (VPS72)
CCC P600
HGNC 11644
MGI 1202305
PubMed 7702631
RGD 1306121
UniProt Q15906
Wiki VPS72
YL1 is highly conserved from humans to yeast. The observations had suggested the location of a transformation suppressor gene(s) on the proximal portion of 1q. Human and mouse YL1 cDNA shared 96% amino acid homology and presumably encoded a transcription factor-like polypeptide. An analysis using a specific antibody demonstrated nuclear localization of YL1 protein. The bacterially expressed YL1 could bind to DNA. Thus, the YL1 protein possibly functions as a transcriptional regulator.epitope-tagged YL1 associated with proteins of the TRRAP/TIP60 (HTATIP) histone acetyltransferase complex in transfected HeLa cells. In addition, YL1 was part of a subset of proteins that also functioned as subunits of the SWI2/SNF2 SMARCA2-related CBP activator protein chromatin remodeling complex.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vacuolar Protein Sorting 72 (VPS72) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vacuolar Protein Sorting 72 (VPS72) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vacuolar Protein Sorting 72 (VPS72) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vacuolar Protein Sorting 72 (VPS72) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vacuolar Protein Sorting 72 (VPS72) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vacuolar Protein Sorting 72 (VPS72) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vacuolar Protein Sorting 72 (VPS72) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vacuolar Protein Sorting 72 (VPS72) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vacuolar Protein Sorting 72 (VPS72) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vacuolar Protein Sorting 72 (VPS72) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vacuolar Protein Sorting 72 (VPS72) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vacuolar Protein Sorting 72 (VPS72) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vacuolar Protein Sorting 72 (VPS72) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vacuolar Protein Sorting 72 (VPS72) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vacuolar Protein Sorting 72 (VPS72) ELISA Kit Customized Service Offer
  1. "Molecular cloning of a novel human cDNA on chromosome 1q21 and its mouse homolog encoding a nuclear protein with DNA-binding ability."Biochem. Biophys. Res. Commun. 208:999-1007(1995) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans."Mol. Cell. Biol. 24:1884-1896(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes."J. Biol. Chem. 280:13665-13670(2005) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  7. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]