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Transmembrane 6 Superfamily, Member 1 (TM6SF1)

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Transmembrane 6 Superfamily, Member 1 (TM6SF1)
CCC P578
HGNC 11860
MGI 1933209
PubMed 11124529
RGD 1307978
UniProt Q9BZW5
By searching an EST database to identify genes on chromosome 15q24-q26, followed by RACE on a fetal brain cDNA library, Carim-Todd et al. (2000) obtained a cDNA encoding TM6SF1. They also identified a paralog, TM6SF2, on chromosome 19p12. The deduced 370-amino acid TM6SF1 protein has 6 transmembrane domains. Northern blot analysis revealed expression of a 1.4-kb TM6SF1 transcript in spleen, testis, and peripheral blood leukocytes.
By genomic sequence analysis, Carim-Todd et al. (2000) determined that the TM6SF1 gene contains 10 exons.By genomic sequence analysis, Carim-Todd et al. (2000) mapped the TM6SF1 gene to chromosome 15q24-q26.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane 6 Superfamily, Member 1 (TM6SF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane 6 Superfamily, Member 1 (TM6SF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane 6 Superfamily, Member 1 (TM6SF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane 6 Superfamily, Member 1 (TM6SF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane 6 Superfamily, Member 1 (TM6SF1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane 6 Superfamily, Member 1 (TM6SF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane 6 Superfamily, Member 1 (TM6SF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane 6 Superfamily, Member 1 (TM6SF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane 6 Superfamily, Member 1 (TM6SF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane 6 Superfamily, Member 1 (TM6SF1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Transmembrane 6 Superfamily, Member 1 (TM6SF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Transmembrane 6 Superfamily, Member 1 (TM6SF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Transmembrane 6 Superfamily, Member 1 (TM6SF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Transmembrane 6 Superfamily, Member 1 (TM6SF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transmembrane 6 Superfamily, Member 1 (TM6SF1) ELISA Kit Customized Service Offer
  1. "Cloning of the novel gene TM6SF1 reveals conservation of clusters of paralogous genes between human chromosomes 15q24-q26 and 19p13.3-p12."Cytogenet. Cell Genet. 90:255-260(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
  4. "TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease."Front. Genet. 5:439-439(2014) [PubMed] [Europe PMC] [Abstract]