Wingless Type MMTV Integration Site Family, Member 11 (WNT11)
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WNT11 is the Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.
WNT11 is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome.
The predicted 354-amino acid protein shared 97%, 85%, and 63% identity with mouse, chicken, and Xenopus Wnt11, respectively. In situ hybridization to embryos indicated that, like mouse Wnt11, human WNT11 is expressed in the tips of ureteric buds and in the perichondrium, a stem cell-like layer that surrounds the future bones and directs their growth and regeneration.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Wingless Type MMTV Integration Site Family, Member 11 (WNT11) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 11 (WNT11) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 11 (WNT11) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEP552Mu | ELISA Kit for Wingless Type MMTV Integration Site Family, Member 11 (WNT11) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPP552Ra01 | Recombinant Wingless Type MMTV Integration Site Family, Member 11 (WNT11) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 11 (WNT11) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 11 (WNT11) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Wingless Type MMTV Integration Site Family, Member 11 (WNT11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Wingless Type MMTV Integration Site Family, Member 11 (WNT11) | ELISA Kit Customized Service Offer |
- "Isolation, characterisation and embryonic expression of WNT11, a gene which maps to 11q13.5 and has possible roles in the development of skeleton, kidney and lung."Gene 219:101-110(1998) [PubMed] [Europe PMC] [Abstract]
- "Molecular cloning and characterization of human WNT11."Int. J. Mol. Med. 8:651-656(2001) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]