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Wingless Type MMTV Integration Site Family, Member 7A (WNT7A)

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Proto-Oncogene Wnt7a Protein

Wingless Type MMTV Integration Site Family, Member 7A (WNT7A)
CCC P547
HGNC 12786
MGI 98961
PubMed 7585966
RGD 69079
UniProt O00755
Wiki WNT7A
WNT7A is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function.The WNT7A gene not only guides the development of the anterior-posterior axis in the female reproductive tract, but also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. WNT7A is also responsive to changes in the levels of sex steroid hormone in the female reproductive tract.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPP547Hu01 Recombinant Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAP547Hu01 Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) WB; IHC; ICC; IP.
MAP547Hu21 Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) WB; IHC; ICC; IP.
Assay Kits SEP547Hu ELISA Kit for Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) Enzyme-linked immunosorbent assay for Antigen Detection.
SCP547Hu CLIA Kit for Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Wingless Type MMTV Integration Site Family, Member 7A (WNT7A) ELISA Kit Customized Service Offer
  1. "Isolation of a full-length human WNT7A gene implicated in limb development and cell transformation, and mapping to chromosome 3p25."Gene 189:25-29(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Isolation, characterization and chromosomal assignment of the human WNT7A gene."Cytogenet. Cell Genet. 74:149-152(1996) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Differential expression of human Wnt genes 2, 3, 4, and 7B in human breast cell lines and normal and disease states of human breast tissue."Cancer Res. 54:2615-2621(1994) [PubMed] [Europe PMC] [Abstract]
  5. "Mutations in WNT7A cause a range of limb malformations, including Fuhrmann syndrome and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndrome."Am. J. Hum. Genet. 79:402-408(2006) [PubMed] [Europe PMC] [Abstract]
  6. "Al-Awadi/Raas-Rothschild syndrome: two new cases and review."Am. J. Med. Genet. A 143:3169-3174(2007) [PubMed] [Europe PMC] [Abstract]
  7. "A novel homozygous Arg222Trp missense mutation in WNT7A in two sisters with severe Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndrome."Am. J. Med. Genet. A 152:2832-2837(2010) [PubMed] [Europe PMC] [Abstract]
  8. "Al-Awadi-Raas-Rothschild (limb/pelvis/uterus-hypoplasia/aplasia) syndrome and WNT7A mutations: genetic homogeneity and nosological delineation."Am. J. Med. Genet. A 155:332-336(2011) [PubMed] [Europe PMC] [Abstract]