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Xylulokinase Homolog (XYLB)

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Xylulose kinase

Xylulokinase Homolog (XYLB)
CCC P543
HGNC 12839
MGI 2142985
RGD 1307372
UniProt O75191
XYLB shares 22% sequence identity with Hemophilus influenzae xylulokinase, and even higher identity to other gene products in C.elegans (45%) and yeast (31-35%), which are thought to belong to a family of enzymes that include fucokinase, gluconokinase, glycerokinase and xylulokinase. These proteins play important roles in energy metabolism.
The 3p22-p21.3 chromosomal region is one of 3 regions of 3p that is commonly deleted in various carcinomas. The XYLB gene contains 18 exons and spans approximately 28 kb. Northern blot analysis revealed that XYLB was expressed as a 2.3-kb major transcript in all tissues tested. A less abundant 1.8-kb mRNA was detected in heart and skeletal muscle.XYLB gene is located between the OCTL2 and ActRIIB genes on 3p22-p21.3.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Xylulokinase Homolog (XYLB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Xylulokinase Homolog (XYLB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Xylulokinase Homolog (XYLB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Xylulokinase Homolog (XYLB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Xylulokinase Homolog (XYLB) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Xylulokinase Homolog (XYLB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Xylulokinase Homolog (XYLB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Xylulokinase Homolog (XYLB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Xylulokinase Homolog (XYLB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Xylulokinase Homolog (XYLB) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Xylulokinase Homolog (XYLB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Xylulokinase Homolog (XYLB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Xylulokinase Homolog (XYLB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Xylulokinase Homolog (XYLB) CLIA Kit Customized Service Offer
n/a ELISA Kit for Xylulokinase Homolog (XYLB) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Genomic structure of a novel human gene (XYLB) on chromosome 3p22-->p21.3 encoding a xylulokinase-like protein."Cytogenet. Cell Genet. 82:101-104(1998) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  7. "Structure and function of human xylulokinase, an enzyme with important roles in carbohydrate metabolism."J. Biol. Chem. 288:1643-1652(2013) [PubMed] [Europe PMC] [Abstract]