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Zinc Finger Protein 117 (ZNF117)

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HPF9; H-plk; Provirus-linked krueppel

Zinc Finger Protein 117 (ZNF117)
CCC P530
HGNC 12897
UniProt Q03924
A zinc finger protein is a DNA-binding protein domain consisting of zinc fingers ranging from two in the Drosophila regulator ADR1, the more common three in mammalian Sp1 up to nine in TFIIIA. They occur in nature as the part of transcription factors conferring DNA sequence specificity as the DNA-binding domain.
They have also found use in protein engineering due to their modularity and have prospects as components of tools for use in therapeutic gene modulation and zinc finger nucleases.
A cluster of Kruppel-type zinc finger genes of the KRAB subclass is located on human chromosome 19p13.1-p12. Bellefroid et al. (1992) reported that ZNF117 (HPF9), a closely related zinc finger gene of that KRAB subfamily, was located on 7q11.2 by in situ hybridization.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 117 (ZNF117) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 117 (ZNF117) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 117 (ZNF117) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 117 (ZNF117) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 117 (ZNF117) ELISA Kit Customized Service Offer
  1. "The human genome contains hundreds of genes coding for finger proteins of the Kruppel type."DNA 8:377-387(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Human proviral mRNAs down regulated in choriocarcinoma encode a zinc finger protein related to Kruppel."Mol. Cell. Biol. 10:4401-4405(1990) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins."Proc. Natl. Acad. Sci. U.S.A. 88:3608-3612(1991) [PubMed] [Europe PMC] [Abstract]