ZMYM3 is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene. The cDNA contains a 4,074-bp ORF encoding a predicted 1,358-amino acid polypeptide.ZNF261 gene is highly conserved among vertebrates and that its expression is most abundant in brain.ZNF261 gene contains 25 exons, including 2 putative alternatively spliced noncoding exons (1A and 1B).
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Zinc Finger, MYM-Type Protein 3 (ZMYM3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Zinc Finger, MYM-Type Protein 3 (ZMYM3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Zinc Finger, MYM-Type Protein 3 (ZMYM3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Zinc Finger, MYM-Type Protein 3 (ZMYM3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Zinc Finger, MYM-Type Protein 3 (ZMYM3) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Zinc Finger, MYM-Type Protein 3 (ZMYM3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Zinc Finger, MYM-Type Protein 3 (ZMYM3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Zinc Finger, MYM-Type Protein 3 (ZMYM3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Zinc Finger, MYM-Type Protein 3 (ZMYM3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Zinc Finger, MYM-Type Protein 3 (ZMYM3) | ELISA Kit Customized Service Offer |
- "Cloning and characterization of DXS6673E, a candidate gene for X-linked mental retardation in Xq13.1."Hum. Mol. Genet. 5:887-897(1996) [PubMed] [Europe PMC] [Abstract]
- "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 4:141-150(1997) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes."J. Biol. Chem. 278:7234-7239(2003) [PubMed] [Europe PMC] [Abstract]
- "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
- "Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration."BMC Biol. 9:54-54(2011) [PubMed] [Europe PMC] [Abstract]
- "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]