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Zinc Finger Protein 41 (ZNF41)

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MRX89

Zinc Finger Protein 41 (ZNF41)
CCC P461
HGNC 13107
PubMed 2037297
UniProt P51814
Wiki ZNF41
Zinc finger domains, loop-like motifs formed by the interaction of 2 invariant pairs of cysteines and histidines with a zinc ion, were first described in transcription factor IIIA in Xenopus oocytes. Franze et al. (1991) isolated a novel human zinc finger gene, ZNF41, from a human X-chromosome-specific library. Nucleotide sequence analysis showed that ZNF41 potentially encodes a polypeptide featuring an array of 18 contiguous zinc fingers of the C2H2 type. Multiple polyadenylated transcripts homologous to ZNF41 are present at different levels in several distinct cell types.
Rosati et al. (1999) reported that ZNF41 contains a KRAB/FPB (Kruppel-associated/finger preceding box) domain, a potent transcription repression motif composed of 2 protein modules, A and B.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 41 (ZNF41) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 41 (ZNF41) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 41 (ZNF41) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 41 (ZNF41) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 41 (ZNF41) ELISA Kit Customized Service Offer
  1. "Coding region intron/exon organization, alternative splicing and X-chromosome inactivation of the KRAB/FPB-domain-containing human zinc finger gene ZNF41."Cytogenet. Cell Genet. 85:291-296(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Isolation and expression analysis of a human zinc finger gene (ZNF41) located on the short arm of the X chromosome."Genomics 9:728-736(1991) [PubMed] [Europe PMC] [Abstract]
  6. "Mutations in the ZNF41 gene are associated with cognitive deficits: identification of a new candidate for X-linked mental retardation."Am. J. Hum. Genet. 73:1341-1354(2003) [PubMed] [Europe PMC] [Abstract]
  7. "XLID-causing mutations and associated genes challenged in light of data from large-scale human exome sequencing."Am. J. Hum. Genet. 93:368-383(2013) [PubMed] [Europe PMC] [Abstract]