≡

Zinc Finger Protein 85 (ZNF85)

[Edit]

HPF4; HTF1

Zinc Finger Protein 85 (ZNF85)
CCC P448
HGNC 13160
PubMed 21593020
UniProt Q03923
Members of the Kruppel zinc finger protein subfamily, which function as transcriptional regulators, are characterized by repeated zinc finger motifs that are connected by conserved H/C link regions.The predicted ZNF85 protein has a small N-terminal nonfinger region followed by a C-terminal domain containing 15 tandemly repeated zinc finger motifs.
The deduced 595-amino acid protein, which contains at least 1 nuclear localization signal in its ZNF91-related spacer region, localizes to the nucleus. ZNF85 binds to DNA in a zinc-dependent manner.ZNF85 KRAB domain exhibits transcriptional repression activity and specifically interacts with several nuclear factors. RNase protection assays demonstrated that ZNF85 is expressed preferentially in testicular tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 85 (ZNF85) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 85 (ZNF85) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 85 (ZNF85) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 85 (ZNF85) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 85 (ZNF85) ELISA Kit Customized Service Offer
  1. "Functional analysis of ZNF85 KRAB zinc finger protein, a member of the highly homologous ZNF91 family."DNA Cell Biol. 17:931-943(1998) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The evolutionarily conserved Kruppel-associated box domain defines a subfamily of eukaryotic multifingered proteins."Proc. Natl. Acad. Sci. U.S.A. 88:3608-3612(1991) [PubMed] [Europe PMC] [Abstract]