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G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C)

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RAIG-3; Retinoic Acid-Induced Gene 3 Protein

G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C)
CCC P427
HGNC 13309
MGI 1917605
PubMed 10945465
RGD 1311408
UniProt Q9NQ84
Wiki GPRC5C
GPRC5C is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene.
The predicted 442-amino acid GPRC5C protein contains 7 predicted transmembrane helices and conserved cysteines characteristic of GPCRs. GPRC5C also has a predicted signal peptide and a potential N-glycosylation site. GPRC5C shares 43% and 42% amino acid identity with GPRC5B and RAIG1 (RAI3).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) CLIA Kit Customized Service Offer
n/a ELISA Kit for G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) CLIA Kit Customized Service Offer
n/a ELISA Kit for G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) CLIA Kit Customized Service Offer
n/a ELISA Kit for G Protein Coupled Receptor, Family C, Group 5, Member C (GPRC5C) ELISA Kit Customized Service Offer
  1. "Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C)."Genomics 67:8-18(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D."Biochim. Biophys. Acta 1518:237-248(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
  5. "Human protein factory for converting the transcriptome into an in vitro-expressed proteome." Nat. Methods 5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
  6. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  8. "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."Science 316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]