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LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction.
The predicted protein contains an N-terminal signal peptide, followed by a cys-rich LY6 domain and a C-terminal hydrophobic region. RT-PCR detected a 378-bp product in all cell lines and fetal and adult tissues tested.LY6G6C gene contains 3 exons and spans about 2.5 kb.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Lymphocyte Antigen 6 Complex, Locus Protein G6C (LY6G6C) | ELISA Kit Customized Service Offer |
- "Genes encoding three new members of the leukocyte antigen 6 superfamily and a novel member of Ig superfamily, together with genes encoding the regulatory nuclear chloride ion channel protein (hRNCC) and an N omega-N omega-dimethylarginine dimethylaminohydrolase homologue, are found in a 30-kb segment of the MHC class III region."J. Immunol. 163:278-287(1999) [PubMed] [Europe PMC] [Abstract]
- "Transcriptional analysis of a novel cluster of LY-6 family members in the human and mouse major histocompatibility complex: five genes with many splice forms."Genomics 80:113-123(2002) [PubMed] [Europe PMC] [Abstract]
- "Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse."Genome Res. 13:2621-2636(2003) [PubMed] [Europe PMC] [Abstract]
- "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Characterization of the five novel Ly-6 superfamily members encoded in the MHC, and detection of cells expressing their potential ligands."Protein Sci. 15:2244-2256(2006) [PubMed] [Europe PMC] [Abstract]