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Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10)

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Gef10

Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10)
CCC P306
HGNC 14103
MGI 2444453
PubMed 20042462
UniProt O15013
Wiki ARHGEF10
ARHGEF10 is a member of the family of Rho guanine nucleotide exchange factors (GEFs), which are implicated in neural morphogenesis and connectivity and regulate the activity of small Rho GTPases by catalyzing the exchange of bound GDP by GTP. The deduced 1,121-amino acid protein shares significant similarity with cell signaling proteins. RT-PCR of several tissues detected relatively weak expression only in testis, lung, kidney, and ovary.
The mouse ARHGEF10 ortholog, Gef10, is highly expressed in the central and peripheral nervous systems. Sequence comparison indicated that the ARHGEF10 signaling pathway is unique to vertebrates. The authors suggested that ARHGEF10 has a role in developmental myelination of peripheral nerves.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10) ELISA Kit Customized Service Offer
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