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Bromodomain And PHD Finger Containing Protein 1 (BRPF1)

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Peregrin; BR140; Bromodomain-Containing Protein 140kD

Bromodomain And PHD Finger Containing Protein 1 (BRPF1)
CCC P293
HGNC 14255
MGI 1926033
PubMed 18469222
RGD 1584828
UniProt P55201
BRPF1 is expressed ubiquitously and at the highest level in testes and spermatogonia. The protein is localized within nuclei, and it is very similar in structure to two zinc finger proteins, AF10 and AF17. It is suggested that these proteins form a family of regulatory proteins. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.BR140 is very similar in structure to 2 other zinc finger genes, AF10 and AF17 (MLLT6), and suggested that they form a family of regulatory proteins.BR140 migrates as a 150-kD protein on SDS-PAGE. Northern blots showed that BR140 is expressed ubiquitously. Western blots and immunohistochemistry revealed that BR140 is expressed at the highest level in testes and spermatogonia, and is localized within nuclei.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bromodomain And PHD Finger Containing Protein 1 (BRPF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bromodomain And PHD Finger Containing Protein 1 (BRPF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bromodomain And PHD Finger Containing Protein 1 (BRPF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bromodomain And PHD Finger Containing Protein 1 (BRPF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bromodomain And PHD Finger Containing Protein 1 (BRPF1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bromodomain And PHD Finger Containing Protein 1 (BRPF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bromodomain And PHD Finger Containing Protein 1 (BRPF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bromodomain And PHD Finger Containing Protein 1 (BRPF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bromodomain And PHD Finger Containing Protein 1 (BRPF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bromodomain And PHD Finger Containing Protein 1 (BRPF1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Bromodomain And PHD Finger Containing Protein 1 (BRPF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Bromodomain And PHD Finger Containing Protein 1 (BRPF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Bromodomain And PHD Finger Containing Protein 1 (BRPF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Bromodomain And PHD Finger Containing Protein 1 (BRPF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bromodomain And PHD Finger Containing Protein 1 (BRPF1) ELISA Kit Customized Service Offer
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  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  7. "ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation."Mol. Cell 21:51-64(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes."Mol. Cell. Biol. 28:6828-6843(2008) [PubMed] [Europe PMC] [Abstract]
  9. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  15. "Solution structure of the bromodomain of peregrin."Submitted (JUN-2006) to the PDB data bank
  16. "Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1."Nat. Struct. Mol. Biol. 17:617-619(2010) [PubMed] [Europe PMC] [Abstract]
  17. "Structural and histone binding ability characterizations of human PWWP domains."PLoS ONE 6:E18919-E18919(2011) [PubMed] [Europe PMC] [Abstract]