RAB26, Member RAS Oncogene Family (RAB26)

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Ras-related protein Rab-26

RAB26, Member RAS Oncogene Family (RAB26)
Members of the RAB protein family are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling. Seki et al. (2000) identified a new member of the RAB family of genes through a search of a public database, and isolated its full-length cDNA from a human fetal brain cDNA library. The deduced 190-amino acid protein shares 87% sequence identity with rat RAB26. By RT-PCR, Seki et al. (2000) demonstrated that RAB26 is predominantly expressed in adult and fetal brain, with high expression in the amygdala, cerebellum, caudate nucleus, and hippocampus. RAB26 gene contains 8 exons that span about 44 kb of genomic DNA.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB26, Member RAS Oncogene Family (RAB26) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB26, Member RAS Oncogene Family (RAB26) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB26, Member RAS Oncogene Family (RAB26) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB26, Member RAS Oncogene Family (RAB26) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB26, Member RAS Oncogene Family (RAB26) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB26, Member RAS Oncogene Family (RAB26) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB26, Member RAS Oncogene Family (RAB26) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB26, Member RAS Oncogene Family (RAB26) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB26, Member RAS Oncogene Family (RAB26) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB26, Member RAS Oncogene Family (RAB26) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant RAB26, Member RAS Oncogene Family (RAB26) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to RAB26, Member RAS Oncogene Family (RAB26) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to RAB26, Member RAS Oncogene Family (RAB26) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for RAB26, Member RAS Oncogene Family (RAB26) CLIA Kit Customized Service Offer
n/a ELISA Kit for RAB26, Member RAS Oncogene Family (RAB26) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "cDNA cloning of a human RAB26-related gene encoding a Ras-like GTP-binding protein on chromosome 16p13.3 region."J. Hum. Genet. 45:309-314(2000) [PubMed] [Europe PMC] [Abstract]
  5. "RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation."Mol. Cell. Biol. 30:1269-1284(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Rab26 modulates the cell surface transport of alpha2-adrenergic receptors from the Golgi."J. Biol. Chem. 287:42784-42794(2012) [PubMed] [Europe PMC] [Abstract]
  7. "Crystal structure of human RAB26 in complex with a GTP analogue."Submitted (FEB-2009) to the PDB data bank