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X Antigen Family, Member 3 (XAGE3)

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PLAC6; GAGED4; XAGE-3; pp9012; CT12.3a; CT12.3b; Cancer/Testis Antigen Family 12,Member 3a; Placenta-Specific 6; G Antigen Family D 4

X Antigen Family, Member 3 (XAGE3)
CCC P225
HGNC 14618
UniProt Q8WTP9
XAGE3 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR.
By homology walking using the dbEST database, Brinkmann et al. (1999) identified XAGE3, which was found in placenta and liver/spleen cDNA libraries. The deduced protein contains 111 amino acids.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant X Antigen Family, Member 3 (XAGE3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to X Antigen Family, Member 3 (XAGE3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to X Antigen Family, Member 3 (XAGE3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for X Antigen Family, Member 3 (XAGE3) CLIA Kit Customized Service Offer
n/a ELISA Kit for X Antigen Family, Member 3 (XAGE3) ELISA Kit Customized Service Offer
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  2. "Large-scale cDNA transfection screening for genes related to cancer development and progression." Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]