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Zinc Finger Protein 333 (ZNF333)

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Zinc Finger Protein 333 (ZNF333)
CCC P185
HGNC 15624
UniProt Q96JL9
ZNF333 recognized the specific DNA core binding sequence ATAAT. ZNF333 repressed transcription of promoters containing the ATAAT sequence in a luciferase reporter assay.
The deduced 665-amino acid protein has a calculated molecular mass of 75.5 kD and shares 44% amino acid identity with ZNF157. ZNF333 has 10 C2H2 zinc finger motifs at the C terminus and 2 N-terminal KRAB domains, both containing KRAB A and KRAB B domains. EST database analysis and RT-PCR identified a splice variant with 174 amino acids, only 1 KRAB domain, and lacking zinc finger motifs. Northern blot analysis of human tissues detected a 4.6-kb transcript with strong expression in heart, moderate expression in liver, skeletal muscle, kidney, and pancreas, and low expression in placenta.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Zinc Finger Protein 333 (ZNF333) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Zinc Finger Protein 333 (ZNF333) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Zinc Finger Protein 333 (ZNF333) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Zinc Finger Protein 333 (ZNF333) CLIA Kit Customized Service Offer
n/a ELISA Kit for Zinc Finger Protein 333 (ZNF333) ELISA Kit Customized Service Offer
  1. "Characterization of ZNF333, a novel double KRAB domain containing zinc finger gene on human chromosome 19p13.1."Biochim. Biophys. Acta 1577:121-125(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 8:85-95(2001) [PubMed] [Europe PMC] [Abstract]