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Solute Carrier Family 17, Member 9 (SLC17A9)

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C20orf59

Solute Carrier Family 17, Member 9 (SLC17A9)
CCC P125
HGNC 16192
MGI 1919107
PubMed 18375752
RGD 1311940
UniProt Q9BYT1
SLC17A9, which encodes a deduced 430-amino acid protein with 12 transmembrane domains. Northern blot analysis of mouse and human tissues detected wide SLC17A9 expression, with highest levels in adrenal gland, brain, and thyroid gland. Immunohistochemical analysis localized Slc17a9 to chromaffin granules in mouse adrenal medulla. SDS-PAGE of human SLC17A9 expressed in insect cells revealed proteins of 63 and 68 kD. Proteoliposomes containing purified human SLC17A9 actively took up ATP, ADP, and GTP using membrane potential as the driving force. ATP uptake was Cl- dependent, and the properties of ATP transport were similar to those found in synaptic vesicles and chromaffin granules. Suppression of endogenous Slc17a9 in a rat pheochromocytoma cell line decreased exocytosis of ATP.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 17, Member 9 (SLC17A9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 17, Member 9 (SLC17A9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 17, Member 9 (SLC17A9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 17, Member 9 (SLC17A9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 17, Member 9 (SLC17A9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 17, Member 9 (SLC17A9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 17, Member 9 (SLC17A9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 17, Member 9 (SLC17A9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 17, Member 9 (SLC17A9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 17, Member 9 (SLC17A9) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Solute Carrier Family 17, Member 9 (SLC17A9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Solute Carrier Family 17, Member 9 (SLC17A9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Solute Carrier Family 17, Member 9 (SLC17A9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Solute Carrier Family 17, Member 9 (SLC17A9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Solute Carrier Family 17, Member 9 (SLC17A9) ELISA Kit Customized Service Offer
  1. "Identification of a vesicular nucleotide transporter."Proc. Natl. Acad. Sci. U.S.A. 105:5683-5686(2008) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones."DNA Res. 10:49-57(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Exome sequencing identifies SLC17A9 pathogenic gene in two Chinese pedigrees with disseminated superficial actinic porokeratosis." J. Med. Genet. 51:699-704(2014) [PubMed] [Europe PMC] [Abstract]