![WD Repeat Containing Domain Protein 17 (WDR17)](/upload/item/img/WD-Repeat-Containing-Domain-Protein-17-(WDR17)-83074.jpg)
The deduced 1,322-amino acid protein has a calculated molecular mass of 147.7. The N terminus contains an approximately 600-amino acid domain containing up to 12 WD repeats that likely adopts a beta-propeller-like structure. The C-terminal 632 amino acids contains an N-glycosylation site, 6 N-myristoylation sites, and numerous phosphorylation sites. Alternatively spliced transcripts include one lacking exon 2, encoding a deduced 1,298-amino acid protein that initiates at an internal methionine, and another in which in-frame skipping of exon 13 generates a deduced 1,270-amino acid protein. Northern blot analysis detected a 7-kb transcript in retina. RT-PCR detected highest WDR17 expression in retina and testis, with lower levels in adult and fetal brain, spinal cord, bone marrow, thymus, colon, skeletal muscle, and uterus.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant WD Repeat Containing Domain Protein 17 (WDR17) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to WD Repeat Containing Domain Protein 17 (WDR17) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to WD Repeat Containing Domain Protein 17 (WDR17) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for WD Repeat Containing Domain Protein 17 (WDR17) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for WD Repeat Containing Domain Protein 17 (WDR17) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant WD Repeat Containing Domain Protein 17 (WDR17) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to WD Repeat Containing Domain Protein 17 (WDR17) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to WD Repeat Containing Domain Protein 17 (WDR17) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for WD Repeat Containing Domain Protein 17 (WDR17) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for WD Repeat Containing Domain Protein 17 (WDR17) | ELISA Kit Customized Service Offer |
- "Cloning and characterization of WDR17, a novel WD repeat-containing gene on chromosome 4q34."Biochim. Biophys. Acta 1579:18-25(2002) [PubMed] [Europe PMC] [Abstract]
- "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Mapping of transcription start sites of human retina expressed genes."BMC Genomics 8:42-42(2007) [PubMed] [Europe PMC] [Abstract]