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KUA contains an N-terminal KUA domain and a C-terminal UEV1 domain. Like KUA, epitope-tagged KUA/UEV1 was expressed in the cytoplasm of transfected COS-7 cells and appeared to localize to the endoplasmic reticulum. In contrast, epitope-tagged UEV1 was expressed in COS-7 cell nuclei.
The deduced 270-amino acid protein contains 2 transmembrane domains and 2 histidine-rich motifs characteristic of fatty acid hydrolases. RT-PCR detected KUA in all human cell lines examined. Epitope-tagged KUA was expressed in the cytoplasm of transfected COS-7 cells, and it appeared to localize to the endoplasmic reticulum. Phylogenetic analysis identified KUA homologs in all species examined except yeast.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Transmembrane Protein 189 (TMEM189) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 189 (TMEM189) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Transmembrane Protein 189 (TMEM189) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Transmembrane Protein 189 (TMEM189) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transmembrane Protein 189 (TMEM189) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Transmembrane Protein 189 (TMEM189) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 189 (TMEM189) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Transmembrane Protein 189 (TMEM189) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Transmembrane Protein 189 (TMEM189) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transmembrane Protein 189 (TMEM189) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Transmembrane Protein 189 (TMEM189) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Transmembrane Protein 189 (TMEM189) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Transmembrane Protein 189 (TMEM189) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Transmembrane Protein 189 (TMEM189) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Transmembrane Protein 189 (TMEM189) | ELISA Kit Customized Service Offer |
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