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Keratin Associated Protein 1-3 (KRTAP1-3)

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KAP1.3

Keratin Associated Protein 1-3 (KRTAP1-3)
CCC P055
HGNC 16771
UniProt Q8IUG1
KRTAP1-3 is a member of the keratin-associated protein (KAP) family.KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21.
The deduced 167-amino acid protein has a calculated molecular mass of 17.1 kD. KAP1.3 is classified as a high sulfur protein owing to a cysteine content of 25.7 mol %. It contains 2 unique motifs conserved among KAP1 family members, several characteristic pentapeptide repeats, and a 20-amino acid subdomain that was conserved among KAP1 family members in all species examined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Keratin Associated Protein 1-3 (KRTAP1-3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Keratin Associated Protein 1-3 (KRTAP1-3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Keratin Associated Protein 1-3 (KRTAP1-3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Keratin Associated Protein 1-3 (KRTAP1-3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Keratin Associated Protein 1-3 (KRTAP1-3) ELISA Kit Customized Service Offer
  1. "Cloning and structural characterization of human hair sulfur-rich keratin genes."Mol. Biol. (Mosk.) 26:550-555(1992)
  2. "Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21."J. Biol. Chem. 276:19440-19451(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Polymorphisms in the human high sulfur hair keratin-associated protein 1, KAP1, gene family."J. Biol. Chem. 277:45493-45501(2002) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]