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KRTAP1-5 is a member of the keratin-associated protein (KAP) family. This protein is a member of the high sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21.The deduced 174-amino acid protein has a calculated molecular mass of 18.0 kD.
KAP1.5 is classified as a high sulfur protein owing to a cysteine content of 24.1 mol %. It contains 2 unique motifs conserved among KAP1 family members, several characteristic pentapeptide repeats, and a 20-amino acid subdomain that was conserved among KAP1 family members in all species examined. In situ hybridization to cryosections of human scalp epidermis showed expression of KAP1.5 in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Keratin Associated Protein 1-5 (KRTAP1-5) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Keratin Associated Protein 1-5 (KRTAP1-5) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Keratin Associated Protein 1-5 (KRTAP1-5) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Keratin Associated Protein 1-5 (KRTAP1-5) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Keratin Associated Protein 1-5 (KRTAP1-5) | ELISA Kit Customized Service Offer |
- "Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21."J. Biol. Chem. 276:19440-19451(2001) [PubMed] [Europe PMC] [Abstract]
- "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage." Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]