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Prickle Homolog 4 (PRICKLE4)

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OEBT; OBTP; C6orf49; TOMM6; Prickle-like protein 4; Overexpressed breast tumor protein

Prickle Homolog 4 (PRICKLE4)
CCC P050
HGNC 16805
MGI 2685785
PubMed 16344560
UniProt Q2TBC4
Wiki C6orf49
C6ORF49 is a member of the LIM domain protein family. C6ORF49 gene contains 9 exons and spans 8.585 kb. By database searching with human PRICKLE1 and PRICKLE2 as probes, Teufel et al. (2005) identified C6ORF49, which they called OEBT, and used this sequence to identify the mouse and rat homologs.
The deduced 385-amino acid C6ORF49 protein shares 72% and 54% sequence identity with the mouse and rat homologs, respectively. C6ORF49 contains 2 LIM domains and a PET domain. It is predicted to be localized in the nucleus. EST database analysis revealed C6ORF49 expression in a broad range of normal tissues as well as in hepatocellular carcinoma, breast cancer, and prostate cancer tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prickle Homolog 4 (PRICKLE4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prickle Homolog 4 (PRICKLE4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prickle Homolog 4 (PRICKLE4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prickle Homolog 4 (PRICKLE4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prickle Homolog 4 (PRICKLE4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Prickle Homolog 4 (PRICKLE4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Prickle Homolog 4 (PRICKLE4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Prickle Homolog 4 (PRICKLE4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Prickle Homolog 4 (PRICKLE4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Prickle Homolog 4 (PRICKLE4) ELISA Kit Customized Service Offer
  1. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Characterization of OEBT, a LIM protein."Int. J. Mol. Med. 15:513-518(2005) [PubMed] [Europe PMC] [Abstract]