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SH2 Domain Containing Protein 3C (SH2D3C)

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NSP3; SHEP1; Novel SH2 Containing Protein-3; SH2 domain-containing Eph receptor-binding protein 1

SH2 Domain Containing Protein 3C (SH2D3C)
CCC P040
HGNC 16884
MGI 1351631
PubMed 24138668
RGD 1307287
UniProt Q8N5H7
Wiki SH2D3C
Adaptor proteins mediate the interaction between membrane receptors and transcription factors through 1 or more domains in the adaptor protein.
By searching an EST database for sequences with signal transduction motifs, Lu et al. (1999) identified a cDNA encoding a deduced 698-amino acid protein, which they named NSP3 (novel SH2-containing protein-3). Sequence analysis revealed that NSP3 also contains a potential SH3 interaction domain. Northern blot analysis detected significant levels of a 3.2- and a 3.8-kb NSP3 transcript in a wide variety of tissues.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SH2 Domain Containing Protein 3C (SH2D3C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SH2 Domain Containing Protein 3C (SH2D3C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SH2 Domain Containing Protein 3C (SH2D3C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SH2 Domain Containing Protein 3C (SH2D3C) CLIA Kit Customized Service Offer
n/a ELISA Kit for SH2 Domain Containing Protein 3C (SH2D3C) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SH2 Domain Containing Protein 3C (SH2D3C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SH2 Domain Containing Protein 3C (SH2D3C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SH2 Domain Containing Protein 3C (SH2D3C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SH2 Domain Containing Protein 3C (SH2D3C) CLIA Kit Customized Service Offer
n/a ELISA Kit for SH2 Domain Containing Protein 3C (SH2D3C) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant SH2 Domain Containing Protein 3C (SH2D3C) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to SH2 Domain Containing Protein 3C (SH2D3C) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to SH2 Domain Containing Protein 3C (SH2D3C) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for SH2 Domain Containing Protein 3C (SH2D3C) CLIA Kit Customized Service Offer
n/a ELISA Kit for SH2 Domain Containing Protein 3C (SH2D3C) ELISA Kit Customized Service Offer
  1. "NSP1 defines a novel family of adaptor proteins linking integrin and tyrosine kinase receptors to the c-Jun N-terminal kinase/stress-activated protein kinase signaling pathway."J. Biol. Chem. 274:10047-10052(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling."Nat. Struct. Mol. Biol. 18:1381-1387(2011) [PubMed] [Europe PMC] [Abstract]