EMG1 Nucleolar Protein Homolog (EMG1)
[Edit]C2F; NEP1; Grcc2f; Ribosomal RNA small subunit methyltransferase NEP1; 18S rRNA (pseudouridine(1248)-N1)-methyltransferase; Ribosome biogenesis protein NEP1
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EMG1 encodes an essential, conserved eukaryotic protein involved in ribosome biogenesis. Emg1 localized to both nuclear and cytoplasmic fractions in the presence of Nop14 but to the cytoplasmic fraction only in Nop14-depleted cells.
Conditional Emg1 double-mutant yeast displayed hypersensitivity to aminoglycoside antibiotics, which affect protein translation, suggesting that Emg1 may play a role in RNA processing or ribosome biogenesis. Pulse-chase labeling of ribosomal RNA transcript processing in conditional Emg1 double-mutant yeast showed a processing defect characterized by increased levels of 35S precursor and reduced levels of 18S rRNA and its 20S precursor.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant EMG1 Nucleolar Protein Homolog (EMG1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to EMG1 Nucleolar Protein Homolog (EMG1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to EMG1 Nucleolar Protein Homolog (EMG1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for EMG1 Nucleolar Protein Homolog (EMG1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for EMG1 Nucleolar Protein Homolog (EMG1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant EMG1 Nucleolar Protein Homolog (EMG1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to EMG1 Nucleolar Protein Homolog (EMG1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to EMG1 Nucleolar Protein Homolog (EMG1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for EMG1 Nucleolar Protein Homolog (EMG1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for EMG1 Nucleolar Protein Homolog (EMG1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant EMG1 Nucleolar Protein Homolog (EMG1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to EMG1 Nucleolar Protein Homolog (EMG1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to EMG1 Nucleolar Protein Homolog (EMG1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for EMG1 Nucleolar Protein Homolog (EMG1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for EMG1 Nucleolar Protein Homolog (EMG1) | ELISA Kit Customized Service Offer |
- "Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination."Genome Res. 7:268-280(1997) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]