Zucman-Rossi et al. (1996) sequenced 40 kb of DNA on a chromosome 22 cosmid and identified 2 new genes, GAR22 (GAS2L1) and RRP22. The RRP22 gene sequence predicts a 202-amino acid polypeptide, which is closely related to members of the Ras superfamily. Northern blot analysis detected a 1.4-kb mRNA expressed only in brain.GAR22-alpha protein was not detected. Imunofluorescence and colocalization experiments in COS-7 cells, demonstrated that both GAR22-beta and GAR17-beta may crosslink microfilaments and microtubules.
Zucman-Rossi et al. (1996) mapped the RRP22 and GAR22 genes between the EWS and BAM22 loci on chromosome 22q12.Zucman-Rossi et al. (1996) determined that the RRP22 gene contains 3 exons.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ras Like Family 10, Member A (RASL10A) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ras Like Family 10, Member A (RASL10A) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ras Like Family 10, Member A (RASL10A) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ras Like Family 10, Member A (RASL10A) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ras Like Family 10, Member A (RASL10A) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ras Like Family 10, Member A (RASL10A) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ras Like Family 10, Member A (RASL10A) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ras Like Family 10, Member A (RASL10A) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ras Like Family 10, Member A (RASL10A) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ras Like Family 10, Member A (RASL10A) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Ras Like Family 10, Member A (RASL10A) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Ras Like Family 10, Member A (RASL10A) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Ras Like Family 10, Member A (RASL10A) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Ras Like Family 10, Member A (RASL10A) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Ras Like Family 10, Member A (RASL10A) | ELISA Kit Customized Service Offer |
- "Identification of new members of the Gas2 and Ras families in the 22q12 chromosome region."Genomics 38:247-254(1996) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of human chromosome 22." Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "RRP22 is a farnesylated, nucleolar, Ras-related protein with tumor suppressor potential."Cancer Res. 65:3117-3125(2005) [PubMed] [Europe PMC] [Abstract]