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Exocyst Complex Component 6B (EXOC6B)

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SEC15L2; SEC15B; SEC15-like protein 2

Exocyst Complex Component 6B (EXOC6B)
CCC P004
HGNC 17085
MGI 1923164
PubMed 18492870
UniProt Q9Y2D4
In yeast and rat, Sec15 is part of a multiprotein complex that is required for targeted exocytosis. The deduced protein contains 710 amino acids, and the 3-prime untranslated region of the mRNA contains 4 MIR sequences. SEC15B shares 69.2% amino acid identity over 668 amino acids with rat Sec15.
RT-PCR ELISA detected low to moderate expression in most tissues and specific adult brain regions tested. Highest expression was detected in testis, ovary, and amygdala. Little or no expression was detected in skeletal muscle, pancreas, spleen, fetal liver, and fetal brain. Bat brain synaptosome Sec15b associated with RalA in a GTP-dependent manner as part of an exocyst complex.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Exocyst Complex Component 6B (EXOC6B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Exocyst Complex Component 6B (EXOC6B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Exocyst Complex Component 6B (EXOC6B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Exocyst Complex Component 6B (EXOC6B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Exocyst Complex Component 6B (EXOC6B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Exocyst Complex Component 6B (EXOC6B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Exocyst Complex Component 6B (EXOC6B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Exocyst Complex Component 6B (EXOC6B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Exocyst Complex Component 6B (EXOC6B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Exocyst Complex Component 6B (EXOC6B) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:63-70(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene."J. Biol. Chem. 276:29792-29797(2001) [PubMed] [Europe PMC] [Abstract]
  5. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]