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Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2)

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SALM1; FIGLER2; Fibronectin Type III,Immunoglobulin And Leucine Rich Repeat Domains 2; Synaptic adhesion-like molecule 1

Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2)
CCC N972
HGNC 21226
MGI 1917780
PubMed 16828986
RGD 1311831
UniProt Q9ULH4
In specific brain regions tested, LRFN2 showed moderate expression in amygdala, corpus callosum, cerebellum, caudate nucleus, hippocampus, substantia nigra, subthalamic nucleus, thalamus, and fetal brain.
The deduced 788-amino acid mouse protein has a predicted signal peptide, a leucine-rich N-terminal domain, 6 leucine-rich repeat domains, a leucine-rich C-terminal domain, Ig C2-like domain (IgC2), a fibronectin type III domain, transmembrane region, and an ESTV PDZ-binding motif. The SALM family members share similarity with proteins of the Slit family, the Amigo family (AMIGO1), and the Nogo66 receptor (RTN4R). Lrfn2 localized to membrane fractions and to postsynaptic density fractions.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Leucine Rich Repeat And Fibronectin Type III Domain Containing Protein 2 (LRFN2) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 6:337-345(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "SALM synaptic cell adhesion-like molecules regulate the differentiation of excitatory synapses."Neuron 50:233-245(2006) [PubMed] [Europe PMC] [Abstract]