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Ankyrin Repeat Domain Protein 11 (ANKRD11)

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LZ16; T13; ANCO1; Ankyrin repeat-containing cofactor 1

Ankyrin Repeat Domain Protein 11 (ANKRD11)
CCC N962
HGNC 21316
MGI 1924337
PubMed 21782149
RGD 1306679
UniProt Q6UB99
ANKRD11 is a member of a family of ankyrin repeat-containing cofactors that interacts with p160 nuclear receptor coactivators and inhibits ligand-dependent transcriptional activation.
The deduced 2,663-amino acid protein had a calculated molecular mass of 298 kD and contained five 33-amino acid ankyrin repeats, a highly charged central region, and many putative nuclear localization signals.ANCO1 is identical to the previously isolated nasopharyngeal carcinoma susceptibility protein LZ16. Smaller transcripts of 3.5 and 7.5 kb were detected. Immunofluorescence studies localized ANCO1 to discrete nuclear foci that colocalized with histone deacetylaces HDAC3, HDAC4, and HDAC5 specifically.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ankyrin Repeat Domain Protein 11 (ANKRD11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ankyrin Repeat Domain Protein 11 (ANKRD11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ankyrin Repeat Domain Protein 11 (ANKRD11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ankyrin Repeat Domain Protein 11 (ANKRD11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ankyrin Repeat Domain Protein 11 (ANKRD11) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ankyrin Repeat Domain Protein 11 (ANKRD11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ankyrin Repeat Domain Protein 11 (ANKRD11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ankyrin Repeat Domain Protein 11 (ANKRD11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ankyrin Repeat Domain Protein 11 (ANKRD11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ankyrin Repeat Domain Protein 11 (ANKRD11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ankyrin Repeat Domain Protein 11 (ANKRD11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ankyrin Repeat Domain Protein 11 (ANKRD11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ankyrin Repeat Domain Protein 11 (ANKRD11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ankyrin Repeat Domain Protein 11 (ANKRD11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ankyrin Repeat Domain Protein 11 (ANKRD11) ELISA Kit Customized Service Offer
  1. "Identification of a novel family of ankyrin repeats-containing cofactors for p160 nuclear receptor coactivators."J. Biol. Chem. 279:33799-33805(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  8. "Mutations in ANKRD11 cause KBG syndrome, characterized by intellectual disability, skeletal malformations, and macrodontia."Am. J. Hum. Genet. 89:289-294(2011) [PubMed] [Europe PMC] [Abstract]
  9. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]