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KH Homology Domain Containing Protein 1 (KHDC1)

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NDG1; C6orf148

KH Homology Domain Containing Protein 1 (KHDC1)
CCC N957
HGNC 21366
PubMed 19129511
UniProt Q4VXA5
By searching for genes similar to the 3 mouse Khdc1 genes, Pierre et al. (2007) identified a family of related genes in eutharian mammals. In human, this family includes KHDC1, DPPA5, OOEP, and ECAT1. The proteins encoded by these genes contain an atypical KH domain with amino acid changes at critical sites, suggesting that it may not bind RNA like canonical KH domains.
In mouse, the 3 Khdc1 genes map to chromosome 1A4.Pierre et al. (2007) identified a family of KHDC1-related genes in eutherian mammals, but not in fish, bird, or opossum. These genes map to a single syntenic region in human, chimpanzee, macaque, dog, and bovine, but a paracentric inversion separated the genes in mouse and rat.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant KH Homology Domain Containing Protein 1 (KHDC1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to KH Homology Domain Containing Protein 1 (KHDC1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to KH Homology Domain Containing Protein 1 (KHDC1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for KH Homology Domain Containing Protein 1 (KHDC1) CLIA Kit Customized Service Offer
n/a ELISA Kit for KH Homology Domain Containing Protein 1 (KHDC1) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Atypical structure and phylogenomic evolution of the new eutherian oocyte-and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family."Genomics 90:583-594(2007) [PubMed] [Europe PMC] [Abstract]