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Nanos Homolog 3 (NANOS3)

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NANOS1L; NOS3

Nanos Homolog 3 (NANOS3)
CCC N913
HGNC 22048
MGI 2675387
PubMed 19861488
RGD 1306672
UniProt P60323
Nanos3contains a zinc finger motif. Nanos3 was expressed in male mouse gonads, in primordial germ cells (PGCs), in bipotential gonads at embryonic day (E) 11.5, and in female gonads at E12.5.
Tsuda et al. (2003) found that Nanos3-null mice were viable and showed no apparent abnormalities, but the size of ovaries and testes in Nanos3-null mice was greatly reduced. Morphologic examination revealed only a few germ cells in the E12.5 genital ridge, and none were found in adult gonads. The specification and derivation of PGCs appeared normal, but PGCs were not subsequently maintained during migration. Apoptosis did not appear to cause the depletion of PGCs in Nanos3-null embryos.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nanos Homolog 3 (NANOS3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nanos Homolog 3 (NANOS3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nanos Homolog 3 (NANOS3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nanos Homolog 3 (NANOS3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nanos Homolog 3 (NANOS3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nanos Homolog 3 (NANOS3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nanos Homolog 3 (NANOS3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nanos Homolog 3 (NANOS3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nanos Homolog 3 (NANOS3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nanos Homolog 3 (NANOS3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nanos Homolog 3 (NANOS3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nanos Homolog 3 (NANOS3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nanos Homolog 3 (NANOS3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nanos Homolog 3 (NANOS3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nanos Homolog 3 (NANOS3) ELISA Kit Customized Service Offer
  1. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Normalization and subtraction: two approaches to facilitate gene discovery."Genome Res. 6:791-806(1996) [PubMed] [Europe PMC] [Abstract]
  4. "NANOS3 function in human germ cell development."Hum. Mol. Genet. 20:2238-2250(2011) [PubMed] [Europe PMC] [Abstract]