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A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18)

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ADAMTS21; ADAM Metallopeptidase With Thrombospondin Type 1 Motif 18

A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18)
CCC N900
HGNC 17110
MGI 2442600
PubMed 23356391
RGD 1560118
UniProt Q8TE60
ADAMTS18 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) CLIA Kit Customized Service Offer
n/a ELISA Kit for A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) CLIA Kit Customized Service Offer
n/a ELISA Kit for A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) CLIA Kit Customized Service Offer
n/a ELISA Kit for A Disintegrin And Metalloproteinase With Thrombospondin 18 (ADAMTS18) ELISA Kit Customized Service Offer
  1. "Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains."Gene 283:49-62(2002) [PubMed] [Europe PMC] [Abstract]
  2. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  6. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Identification of ADAMTS18 as a gene mutated in Knobloch syndrome."J. Med. Genet. 48:597-601(2011) [PubMed] [Europe PMC] [Abstract]
  8. "The syndrome of microcornea, myopic chorioretinal atrophy, and telecanthus (MMCAT) is caused by mutations in ADAMTS18."Hum. Mutat. 34:1195-1199(2013) [PubMed] [Europe PMC] [Abstract]
  9. "No evidence for locus heterogeneity in Knobloch syndrome."J. Med. Genet. 50:565-566(2013) [PubMed] [Europe PMC] [Abstract]