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Enhancer Of mRNA Decapping Protein 4 (EDC4)

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RCD-8; Ge-1; HEDLS; Human enhancer of decapping large subunit

Enhancer Of mRNA Decapping Protein 4 (EDC4)
CCC N893
HGNC 17157
MGI 2446249
PubMed 23142987
RGD 1562009
UniProt Q6P2E9
RCD8 promoted the association of DCP1A and DCP2, and overexpressed DCP1A and DCP2 did not associate in its absence. RCD8 associated with DCP2 and stimulated its decapping activity in vitro. The deduced 1,215-amino acid protein contains a central serine-rich region and a putative nuclear localization sequence (NLS) near its C terminus; however, it lacks zinc finger, leucine zipper, and RNA-binding motifs, which are found in other autoantigens. Immunoblot analysis indicated that GE1 is expressed as a 160-kD protein. Epitope mapping analysis suggested that the functional NLS-containing hydrophilic region of GE1 is the site recognized by patient serum. Immunofluorescence microscopy using rat antisera to the recombinant protein demonstrated speckled, mostly nuclear expression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Enhancer Of mRNA Decapping Protein 4 (EDC4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Enhancer Of mRNA Decapping Protein 4 (EDC4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Enhancer Of mRNA Decapping Protein 4 (EDC4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Enhancer Of mRNA Decapping Protein 4 (EDC4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Enhancer Of mRNA Decapping Protein 4 (EDC4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Enhancer Of mRNA Decapping Protein 4 (EDC4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Enhancer Of mRNA Decapping Protein 4 (EDC4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Enhancer Of mRNA Decapping Protein 4 (EDC4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Enhancer Of mRNA Decapping Protein 4 (EDC4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Enhancer Of mRNA Decapping Protein 4 (EDC4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Enhancer Of mRNA Decapping Protein 4 (EDC4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Enhancer Of mRNA Decapping Protein 4 (EDC4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Enhancer Of mRNA Decapping Protein 4 (EDC4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Enhancer Of mRNA Decapping Protein 4 (EDC4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Enhancer Of mRNA Decapping Protein 4 (EDC4) ELISA Kit Customized Service Offer
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