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Proline Rich Protein 3 (PROL3)

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SMR3B; P-B; PRL3; Submaxillary Gland Androgen Regulated Protein 3B

Proline Rich Protein 3 (PROL3)
CCC N862
HGNC 17326
UniProt P02814
By PCR of human submaxillary gland cDNA, Isemura and Saitoh (1994) cloned SMR3B, which they called PBII. SMR3B consists of 22-amino acid secretory signal sequence, cleavage of which results in a mature 57-amino acid protein. Southern blot analysis detected expression in human submaxillary gland, and Southern blot and database analysis indicated that SMR3B was conserved in vertebrates and yeast. Isemura (2000) reported a corrected SMR3B sequence. The author noted that SMR3B is also expressed in human parotid gland.
Isemura (2000) determined that the SMR3B gene contains 3 exons spanning 7.1 kb. The first exon is noncoding, and the third exon encodes the entire mature protein sequence.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Proline Rich Protein 3 (PROL3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Proline Rich Protein 3 (PROL3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proline Rich Protein 3 (PROL3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Proline Rich Protein 3 (PROL3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proline Rich Protein 3 (PROL3) ELISA Kit Customized Service Offer
  1. "Molecular cloning and sequence analysis of cDNA coding for the precursor of the human salivary proline-rich peptide P-B."J. Biochem. 115:1101-1106(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Nucleotide sequence of gene PBII encoding salivary proline-rich protein P-B."J. Biochem. 127:393-398(2000) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Isolation and amino acid sequences of proline-rich peptides of human whole saliva."J. Biochem. 86:79-86(1979) [PubMed] [Europe PMC] [Abstract]
  5. "Large-scale purification and characterization of the major phosphoproteins and mucins of human submandibular-sublingual saliva."Biochem. J. 280:341-352(1991) [PubMed] [Europe PMC] [Abstract]