Axotrophin (AXOT)
[Edit]MARCH7; MARCH-VII; RNF177; Membrane-Associated Ring Finger(C3HC4)7; E3 ubiquitin-protein ligase MARCH7; Membrane-associated RING-CH protein VII
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MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases. MARCH proteins add ubiquitin to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments.
Poxviruses and gamma-2 herpesviruses express ubiquitin ligases called K3 proteins that inhibit the surface expression of glycoproteins, including major histocompatibility complex class I molecules. The deduced MARCH7 protein has a 500-amino acid N-terminal domain, followed by a RING-CH domain and 2 transmembrane domains. Other MARCH proteins lack the N-terminal extension, and the RING-CH domain of MARCH7 is only distantly related to those of other MARCH proteins.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Axotrophin (AXOT) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Axotrophin (AXOT) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Axotrophin (AXOT) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Axotrophin (AXOT) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Axotrophin (AXOT) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Axotrophin (AXOT) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Axotrophin (AXOT) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Axotrophin (AXOT) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Axotrophin (AXOT) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Axotrophin (AXOT) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Axotrophin (AXOT) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Axotrophin (AXOT) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Axotrophin (AXOT) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Axotrophin (AXOT) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Axotrophin (AXOT) | ELISA Kit Customized Service Offer |
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