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G Antigen 12J (GAGE12J)

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GAGE11; G Antigen 11

G Antigen 12J (GAGE12J)
CCC N825
HGNC 17778
UniProt A6NER3
GAGE cancer/testis antigens, including GAGE12J, are frequently expressed in many different types of cancer, whereas their expression in normal tissues is limited to the germ cells of the immune-privileged organs, testis and ovary.The promoters, which are highly conserved within 1.4- to 1.5-kb of the transcription initiation site, are GC-rich and have no TATA boxes. GAGE transcripts are found only in primates.
Gjerstorff and Ditzel (2008) stated that the GAGE12J gene is contained within a 9.5-kb GAGE repeat. The GAGE12J gene contains 5 exons spanning about 6.3 kb and has a LINE insertion.By genomic sequence analysis, Gjerstorff and Ditzel (2008) mapped the GAGE12J gene to a GAGE gene cluster on chromosome Xp11.23.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G Antigen 12J (GAGE12J) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G Antigen 12J (GAGE12J) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G Antigen 12J (GAGE12J) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G Antigen 12J (GAGE12J) CLIA Kit Customized Service Offer
n/a ELISA Kit for G Antigen 12J (GAGE12J) ELISA Kit Customized Service Offer
  1. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  2. "An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members."Tissue Antigens 71:187-192(2008) [PubMed] [Europe PMC] [Abstract]