≡

COBW Domain Containing Protein 2 (CBWD2)

[Edit]

Cobalamin synthase W domain-containing protein 2

COBW Domain Containing Protein 2 (CBWD2)
CCC N807
HGNC 17907
UniProt Q8IUF1
By examining genes arising from intra- and interchromosomal duplications involving the ancestral chromosome 2 fusion site, followed by PCR of a fetal brain cDNA library, Fan et al. (2002) cloned CBWD2. They also identified the paralogs CBWD1 and CBWD3.
No 2 of the 3 CBWD paralogs are identical, but they all encode a deduced 395-amino acid protein containing a cobalamin synthetase W domain.Fan et al. (2002) also identified a CBWD1 splice variant lacking exons 9 and 10.
Fan et al. (2002) determined that the CBWD2 gene contains 15 coding exons and spans 59 kb.By genomic sequence analysis, Fan et al. (2002) mapped the CBWD2 gene to chromosome 2q13-q14.1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant COBW Domain Containing Protein 2 (CBWD2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to COBW Domain Containing Protein 2 (CBWD2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to COBW Domain Containing Protein 2 (CBWD2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for COBW Domain Containing Protein 2 (CBWD2) CLIA Kit Customized Service Offer
n/a ELISA Kit for COBW Domain Containing Protein 2 (CBWD2) ELISA Kit Customized Service Offer
  1. "Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions."Genome Res. 12:1663-1672(2002) [PubMed] [Europe PMC] [Abstract]
  2. "Diverse fates of paralogs following segmental duplication of telomeric genes."Genomics 84:239-247(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]