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Translocase Of Outer Mitochondrial Membrane 40 (TOMM40)

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PEREC1; TOM40; PER-EC1; C19orf1; p38.5; Protein Haymaker; Mitochondrial import receptor subunit TOM40 homolog

Translocase Of Outer Mitochondrial Membrane 40 (TOMM40)
CCC N799
HGNC 18001
MGI 1858259
PubMed 22710912
RGD 1303022
UniProt O96008
TOMM40 is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for protein import into mitochondria.The deduced protein contains 361 amino acids. Fractionation of rat liver detected Tomm40 within the mitochondrial fraction. Extraction and antibody-accessibility studies suggested that Tomm40 is embedded within the mitochondrial membrane.Tomm40 was associated with a 400-kD complex containing the mitochondrial import receptors Tom20 and Tom22 and several smaller components. Mitochondria-targeted preproteins interacted with the Tomm40-containing complex during their transit to the mitochondrial matrix, and immunodepletion of Tomm40 caused the loss of preprotein import activity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) CLIA Kit Customized Service Offer
n/a ELISA Kit for Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) CLIA Kit Customized Service Offer
n/a ELISA Kit for Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) CLIA Kit Customized Service Offer
n/a ELISA Kit for Translocase Of Outer Mitochondrial Membrane 40 (TOMM40) ELISA Kit Customized Service Offer
  1. "Sequencing of 42kb of the APO E-C2 gene cluster reveals a new gene: PEREC1."DNA Seq. 9:89-100(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Genetic identity and differential expression of p38.5 (Haymaker) in human malignant and non-malignant cells."Int. J. Cancer 94:800-806(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. , Submitted (MAR-2007) to UniProtKB
  5. "Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane."J. Biol. Chem. 277:42197-42204(2002) [PubMed] [Europe PMC] [Abstract]
  6. "Dissection of the mitochondrial import and assembly pathway for human Tom40."J. Biol. Chem. 280:11535-11543(2005) [PubMed] [Europe PMC] [Abstract]
  7. "Identification of Tom5 and Tom6 in the preprotein translocase complex of human mitochondrial outer membrane."Biochem. Biophys. Res. Commun. 369:958-963(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]