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TWIST Neighbor (TWISTNB)

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DNA-directed RNA polymerase I subunit RPA43

TWIST Neighbor (TWISTNB)
CCC N793
HGNC 18027
MGI 106292
PubMed 23472213
RGD 1307824
UniProt Q3B726
TWISTNB encodes a deduced 338-amino acid protein with a predicted molecular mass of 37.4 kD. The protein contains 2 potential nuclear localization signals in the C terminus and shares 72% sequence identity with the mouse ortholog. Northern blot analysis revealed expression of a single 4.3-kb transcript in all human fetal and adult tissues tested, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues. RT-PCR analysis detected expression of mouse Twistnb in all adult tissues tested.TWISTNB gene contains 4 exons and spans approximately 13 kb. The 5-prime coding region contains a CpG island.TWISTNB lies approximately 580 kb upstream from the TWIST gene.TWISTNB lies approximately 580 kb upstream from the TWIST gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TWIST Neighbor (TWISTNB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TWIST Neighbor (TWISTNB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TWIST Neighbor (TWISTNB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TWIST Neighbor (TWISTNB) CLIA Kit Customized Service Offer
n/a ELISA Kit for TWIST Neighbor (TWISTNB) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TWIST Neighbor (TWISTNB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TWIST Neighbor (TWISTNB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TWIST Neighbor (TWISTNB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TWIST Neighbor (TWISTNB) CLIA Kit Customized Service Offer
n/a ELISA Kit for TWIST Neighbor (TWISTNB) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TWIST Neighbor (TWISTNB) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TWIST Neighbor (TWISTNB) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TWIST Neighbor (TWISTNB) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TWIST Neighbor (TWISTNB) CLIA Kit Customized Service Offer
n/a ELISA Kit for TWIST Neighbor (TWISTNB) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "Human chromosome 7: DNA sequence and biology." Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Identification and characterisation of the gene TWIST NEIGHBOR (TWISTNB) located in the microdeletion syndrome 7p21 region."Cytogenet. Genome Res. 97:167-170(2002) [PubMed] [Europe PMC] [Abstract]
  5. "Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter."EMBO Rep. 3:1082-1087(2002) [PubMed] [Europe PMC] [Abstract]
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  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]