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BTB/POZ Domain Containing Protein 7 (BTBD7)

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FUP1

BTB/POZ Domain Containing Protein 7 (BTBD7)
CCC N772
HGNC 18269
MGI 1917858
PubMed 20671187
RGD 1306262
UniProt Q9P203
By cDNA/EST microarray analysis, Pan et al. (2001) identified BTBD7, which they called FUP1, as a gene expressed preferentially in hepatocellular carcinoma compared to normal liver. The deduced protein contains a predicted nucleus-targeting motif. Transient transfection of FLAG-tagged FUP1 in NIH3T3 cells confirmed the nuclear localization. Northern blot analysis detected highest expression of FUP1 in heart, with low expression in all other tissues tested.
FUP1-transfected NIH3T3 cells displayed increased cellular proliferation, whereas antisense FUP1-transfected hepatoma cells displayed decreased proliferation. In addition, injection of FUP1-transfected NIH3T3 cells into nude mice induced tumor formation. Pan et al. (2001) concluded that FUP1 stimulates cell proliferation and tumor formation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant BTB/POZ Domain Containing Protein 7 (BTBD7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to BTB/POZ Domain Containing Protein 7 (BTBD7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to BTB/POZ Domain Containing Protein 7 (BTBD7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for BTB/POZ Domain Containing Protein 7 (BTBD7) CLIA Kit Customized Service Offer
n/a ELISA Kit for BTB/POZ Domain Containing Protein 7 (BTBD7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant BTB/POZ Domain Containing Protein 7 (BTBD7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to BTB/POZ Domain Containing Protein 7 (BTBD7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to BTB/POZ Domain Containing Protein 7 (BTBD7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for BTB/POZ Domain Containing Protein 7 (BTBD7) CLIA Kit Customized Service Offer
n/a ELISA Kit for BTB/POZ Domain Containing Protein 7 (BTBD7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant BTB/POZ Domain Containing Protein 7 (BTBD7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to BTB/POZ Domain Containing Protein 7 (BTBD7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to BTB/POZ Domain Containing Protein 7 (BTBD7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for BTB/POZ Domain Containing Protein 7 (BTBD7) CLIA Kit Customized Service Offer
n/a ELISA Kit for BTB/POZ Domain Containing Protein 7 (BTBD7) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:143-150(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Strategy for comprehensive identification of human N-myristoylated proteins using an insect cell-free protein synthesis system."Proteomics 10:1780-1793(2010) [PubMed] [Europe PMC] [Abstract]