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TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX)

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TGIFLX; TGF-beta-induced transcription factor 2-like protein; TGIF-like on the X

TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX)
CCC N725
HGNC 18570
MGI 2387796
UniProt Q8IUE1
TGIF2LX encodes a member of the TALE/TGIF homeobox family of transcription factors. Testis-specific expression suggests that this gene may play a role in spermatogenesis. A homolog of this gene lies within the male specific region of chromosome Y, in a block of sequence that is thought to be the result of a large X-to-Y transposition.
A single basepair deletion in the human TGIFLY (as compared with TGIFLX) created a different reading frame, where the C-terminal residues shared by TGIFLX and other TGIF proteins were missing. The conservation, similarity to protein-encoding transcription factors, and specific expression in testis pointed to a transcriptional role for TGIFLX/Y in this tissue.TGIFLX/Y gene has a 2,666-bp mRNA encoded by 2 exons separated by a 96-bp intron.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX) CLIA Kit Customized Service Offer
n/a ELISA Kit for TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX) CLIA Kit Customized Service Offer
n/a ELISA Kit for TGFB Induced Factor Homeobox 2 Like Protein, X-Linked (TGIF2LX) ELISA Kit Customized Service Offer
  1. "The human-specific Yp11.2/Xq21.3 homology block encodes a potentially functional testis-specific TGIF-like retroposon."Mamm. Genome 13:463-468(2002) [PubMed] [Europe PMC] [Abstract]
  2. "The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes." Nature 423:825-837(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The solution structure of the homeobox domain of human homeobox protein TGIF2LX."Submitted (OCT-2006) to the PDB data bank